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Clinical Trials

The RAFT Trial

In patients with mild to moderate heart failure and a wide QRS complex, the addition of CRT to an ICD reduced rates of death and…

December 16, 2010

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Clinical Trials

The RACE II Trial

In patients with permanent atrial fibrillation, lenient rate control is as effective as strict rate control and is easier to achieve.

April 15, 2010

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Clinical Trials

The MADIT-CRT Trial

CRT combined with ICD decreased the risk of heart-failure events in relatively asymptomatic patients with a low ejection fraction and wide QRS complex.

October 1, 2009

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Clinical Trials

The RE-LY Trial

In patients with AF, dabigatran given at a dose of 110 mg was associated with rates of stroke and systemic embolism that were similar to…

September 17, 2009

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Clinical Trials

The SCD-HeFT Trial

In patients with heart failure and reduced ejection fraction, implantation of an ICD reduces all-cause mortality.

January 20, 2005

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Clinical Trials

The COMPANION Trial

In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy decreases the combined risk of death from any cause or first hospitalization…

May 20, 2004

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Clinical Trials

The DAVID Trial

For patients with standard indications for ICD therapy, no indication for cardiac pacing, and an LVEF of 40% or less, dual-chamber pacing offers no clinical…

December 25, 2002

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Clinical Trials

The AFFIRM Trial

A comparison of rate control and rhythm control in patients with atrial fibrillation.

December 5, 2002

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Clinical Trials

The MOST Trial

For sinus-node dysfunction, while dual-chamber pacing does not improve stroke-free survival compared with ventricular pacing, dual-chamber pacing does reduce the risk of atrial fibrillation, signs…

June 13, 2002

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Clinical Trials

The MADIT II Trial

Implantable cardioverter-defibrillator (ICD) therapy is superior to conventional medical therapy in reducing the risk of death among patients with prior myocardial infarction and reduced ejection…

March 21, 2002